Clinical profile of leukocyte adhesion deficiency type I.
نویسندگان
چکیده
Leukocyte adhesion deficiency type I (LAD-I) is a rare, inherited immunodeficiency with defect in the recruitment of leukocyte to the site of inflammation. Patients with severe LAD-I have absent or markedly reduced expression of CD18 and CD11. Here we report clinical profile of 7 cases of LAD-I diagnosed at our center over a period of 3 years. Recurrent skin and mucous membrane infections were the major presenting manifestations. All children had a history of delayed cord separation.
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ورودعنوان ژورنال:
- Indian pediatrics
دوره 49 1 شماره
صفحات -
تاریخ انتشار 2012